Quick Summary
Adco Contromet Tablet is a medication containing Metoclopramide monohydrochloride, used as an adjunct to X-ray examinations of the stomach and duodenum, for post-operative hypotonia, and as an anti-emetic for various conditions. It is important to note the contraindications, warnings, and precautions associated with its use, including the risk of developing tardive dyskinesia. The recommended dosage, possible side effects, and presentation options are also discussed.
Introduction
Adco Contromet Tablet is a medication that contains Metoclopramide monohydrochloride. It is commonly used as an adjunct to X-ray examinations of the stomach and duodenum, post-operative hypotonia (postvagotomy syndrome), and for preventing and treating nausea and vomiting caused by various factors such as radiation therapy or certain medications.
This blog post aims to provide comprehensive information about Adco Contromet Tablet, including its uses, dosage recommendations, potential side effects, contraindications, warnings/precautions, and frequently asked questions.
Before we delve into the details of this medication’s usage guidelines, it’s important to note that you should always consult with your healthcare professional before starting any new treatment regimen. They will be able to assess your specific medical condition and determine if Adco Contromet Tablet is suitable for you based on their expertise.
In the following sections, you’ll find detailed information regarding different aspects related to Adco Contromet Tablet such as the active ingredient, the pharmacological classification, dosage instructions, safety precautions, and possible side effects. It’s crucially important that you read through all these sections carefully in order to understand how best to take advantage of this medication while minimizing potential risks or complications.
What is Adco Contromet Tablet?
Adco Contromet Tablet is a medication that contains Metoclopramide monohydrochloride. It comes in both tablet and syrup form, providing options for different patient preferences or needs.
The tablet formulation of Adco Contromet contains 10 mg of Metoclopramide monohydrochloride per dose. This dosage strength ensures an effective therapeutic response while minimizing the risk of adverse effects.
On the other hand, the syrup version of Adco Contromet has a lower concentration with each dose containing 5 mg of Metoclopramide monohydrochloride. The presence of sucrose in the syrup provides sweetness to enhance palatability for those who prefer liquid medications.
Both formulations are designed to be easy to swallow and convenient for administration according to individual requirements or medical professional recommendations.
It’s important to note that these tablets do not contain any added sugars, making them suitable for individuals who need sugar-free alternatives due to dietary restrictions or health concerns related to blood glucose levels control.
Pharmacological Classification
Adco Contromet Tablet falls under the pharmacological classification of medicines acting on the gastrointestinal tract. More specifically, it belongs to a class known as gastrointestinal antispasmodics and cholinolytics.
Gastrointestinal Antispasmodics
Gastrointestinal antispasmodics are medications that work by relaxing smooth muscles in the digestive system. They help relieve symptoms such as abdominal pain, cramps, bloating, and spasms associated with various gastrointestinal conditions.
Cholinolytics
Cholinolytics refer to drugs that block or inhibit certain receptors for acetylcholine – a neurotransmitter involved in muscle contractions. By blocking these receptors, cholinolytic medications can reduce excessive stimulation of smooth muscles in the gut and decrease abnormal movements within the digestive system.
In summary, Adco Contromet Tablet is classified as both an antispasmodic agent and a medication that inhibits specific actions mediated by acetylcholine within the GI tract. This dual action helps alleviate discomfort caused by spasticity or hyperactivity of intestinal muscles commonly seen in conditions like irritable bowel syndrome (IBS) or post-operative hypotonia (postvagotomy syndrome).
It’s important to note that this classification provides insight into how Adco Contromet Tablet works at a physiological level but does not encompass all potential uses for which it may be prescribed clinically.
Uses of Adco Contromet Tablet
Adco Contromet Tablet is a medication that serves multiple purposes in the field of medicine. Here are some common uses for this tablet:
1. Adjunct to X-ray Examinations:
- Adco Contromet Tablet is often used as an adjunct during X-ray examinations of the stomach and duodenum.
- It helps enhance visualization by reducing gastrointestinal spasms, allowing for clearer imaging results.
2. Post-Operative Hypotonia (Postvagotomy Syndrome):
- After certain surgical procedures like vagotomy, patients may experience post-operative hypotonia or reduced muscle tone in their digestive system.
- Adco Contromet Tablet can be prescribed to alleviate symptoms associated with this condition.
3. Anti-emetic Properties:
i) Prevention and Treatment of Irradiation Sickness:
- When undergoing radiation therapy, individuals might experience nausea and vomiting known as irradiation sickness.
- The anti-emetic properties present in Adco Contromet help prevent these side effects from occurring or reduce their severity if they do occur.
ii) Post-Operative Vomiting:
Adco Contromet Tablet can also be used to treat post-operative vomiting.
Contraindications
Adco Contromet Tablet is a medication that should be used with caution and avoided in certain cases. Here are the contraindications for using Adco Contromet Tablet:
1. Gastrointestinal Conditions:
- Adco Contromet Tablet should not be used if you have gastrointestinal conditions that might be adversely affected, such as intestinal obstruction or immediately after surgery.
- These conditions can interfere with the normal functioning of your digestive system and may worsen when taking this medication.
2. Phaeochromocytoma:
- Patients diagnosed with phaeochromocytoma, which is a rare tumor of adrenal gland tissue, should avoid using Adco Contromet Tablet.
- This condition involves excessive production of hormones like adrenaline and noradrenaline, which can interact negatively with the active ingredients in this medication.
3. Convulsive Disorders:
- If you have convulsive disorders characterized by recurrent seizures or fits (epilepsy), it is important to avoid using Adco Contomet Tablets.
- The use of metoclopramide-containing medications like Ado Contramot has been associated with an increased risk of seizure activity in patients already prone to convulsions.
It’s crucial to consult your healthcare professional before starting any new medication regimen, including taking Addo Contramot tablets. They will assess your medical history and current health status to determine whether it’s safe for you to take this particular medicine based on these contraindications.
Warnings and Precautions
Adco Contromet Tablet is a medication that comes with important warnings and precautions to ensure safe usage. It is crucial for patients, especially those who fall into specific categories, to be aware of these considerations before starting treatment.
Risk of Tardive Dyskinesia
One significant warning associated with the use of Adco Contromet Tablet is the risk of developing tardive dyskinesia. This condition refers to a serious movement disorder characterized by involuntary repetitive movements such as grimacing or lip smacking.
- The risk increases with prolonged duration of treatment and higher cumulative doses.
- Elderly individuals, particularly elderly women, are more susceptible to developing tardive dyskinesia while using this medication.
- Patients should promptly report any signs or symptoms suggestive of tardive dyskinesia (such as uncontrolled facial movements) so that appropriate action can be taken.
Discontinuation in Case Of Tardive Dyskinesia
If signs or symptoms indicative of tardive dyskinesia develop during therapy with Adco Contromet Tablet, it is essential for patients to discontinue its use immediately under medical supervision.
Special Precautions For Certain Patient Groups
Special care must be exercised when administering Adco Contromet Tablet in certain patient groups due to their increased vulnerability:
a) Children
The safety profile and efficacy data regarding children’s usage may differ from adults’. Therefore special caution should be observed when prescribing this medicine for pediatric populations.
b) Young Patients
Similar attention needs given while treating young adult patients since they might have different responses compared to older age groups.
c) Elderly Individuals
Elderly people are at an elevated risk not only because they tend towards experiencing adverse effects like tardive dyskinesias but also other side-effects related specifically towards them. It becomes necessary for healthcare professionals to take extra precautions while prescribing Adco Contromet Tablet to elderly patients.
Regular Review for Patients on Prolonged Therapy
Patients who are prescribed Adco Contromet Tablet for prolonged periods should be regularly reviewed by their healthcare provider. This allows monitoring of the medication’s effectiveness and assessment of any potential adverse effects that may arise over time.
Potential Drug Interactions
Adco Contromet Tablet has the potential to interact with other medications, leading to extrapyramidal reactions or affecting absorption.
- It is crucial for patients using this medicine concurrently with other drugs known to cause similar movement disorders (extrapyramidal symptoms) to exercise caution.
- Additionally, it is important for individuals taking medicines that can affect drug absorption (e.g., antacids), as they might experience altered efficacy when used in combination with Adco Contromet Tablet.
It is essential for both healthcare professionals and patients alike to understand these warnings and precautions to ensure safe usage of Adco Contromet Tablet in order to preserve patient health and minimize risks associated with its use.
Dosage and Administration
Adco Contromet Tablet should be taken according to the recommended dosage guidelines. It is important to follow these instructions carefully for safe and effective use of the medication.
Recommended Dosage for Adults
For adults, the recommended dosage is 10 mg of Adco Contromet Tablet taken every eight hours. This means that a total daily dose would amount to 30 mg.
Dosage for Diagnostic Procedures
In certain cases where diagnostic radiology or duodenal intubation procedures are being performed, a higher dose may be required. Before undergoing such procedures, it is advised to take a single dose of 20 mg before consuming any barium meal.
Dosage for Children
The appropriate dosage for children varies depending on their age and weight. It is crucial to consult with a healthcare professional who can determine the correct dosing regimen based on individual factors.
It’s essential not to exceed the prescribed dosage without medical supervision as this could lead to adverse effects or complications.
To ensure optimal results from treatment with Adco Contromet Tablet:
- Take each tablet at regular intervals throughout the day – ideally every eight hours unless otherwise directed by your doctor.
- Swallow tablets whole with water; do not crush or chew them as this may affect how they work in your body.
- If you forget a scheduled dose, take it as soon as possible but avoid doubling up doses if too much time has passed since your last one (consult package insert).
- Do not stop taking Adco Contromet suddenly without consulting your healthcare provider first – abrupt discontinuation might cause withdrawal symptoms or worsen underlying conditions requiring its use.
Remember that adherence plays an integral role in achieving desired therapeutic outcomes when using medications like Adco Contromet Tablets.
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Side Effects
Adco Contromet Tablet, like any medication, may cause certain side effects in some individuals. It is important to be aware of these potential side effects and seek medical attention if they occur or worsen. Here are the possible side effects associated with Adco Contromet Tablet:
1. Tardive Dyskinesia
One significant warning associated with the use of Adco Contromet Tablet is the risk of developing tardive dyskinesia. This condition refers to a serious movement disorder that can become irreversible over time. The risk increases with prolonged treatment duration and higher cumulative doses.
2. Extrapyramidal Symptoms
Some patients may experience extrapyramidal symptoms while taking Adco Contromet Tablets. This includes involuntary muscle movements such as tremors, rigidity, restlessness (akathisia), dystonia (abnormal postures), parkinsonism-like symptoms, and other abnormal body movements. These symptoms usually resolve once the medication is discontinued but should be reported to a healthcare professional.
3. Bowel Upsets
Gastrointestinal disturbances such as diarrhea or constipation have been reported by some users of Adco Contromet tablets. It’s advisable for patients experiencing persistent bowel upsets after starting this medicine to consult their doctor immediately.
4. Drowsiness, Fatigue, Dizziness & Restlessness
These common central nervous system-related adverse reactions might affect your ability to drive vehicles, machinery, or perform hazardous tasks. Patients who feel drowsy, fatigued, dizzy, or restless during therapy must avoid activities requiring mental alertness until it subsides completely.
5. Anxiety
Anxiety has also been observed in rare cases among those using Adco Contromet Tablet. If you notice an increase in anxiety levels, it would be best advised consulting your physician about alternative medications available on the market which do not produce a similar effect.
6. Galactorrhea & Gynecomastia
Adco Contromet Tablet may cause an increase in prolactin levels, leading to galactorrhea (abnormal breast milk production) and gynecomastia (enlargement of male breasts). If you experience these symptoms while taking the medication, it is important to consult your healthcare provider.
7. Transient Increases in Plasma Aldosterone Concentrations
Some patients using Adco Contromet Tablet have reported transient increases in plasma aldosterone concentrations. This can lead to fluid retention, hypertension, or even heart failure. It’s advisable for those experiencing such side effects to seek immediate medical attention.
8. Hypertensive Crises
Patients with phaeochromocytoma, a rare tumor that affects adrenal glands, may be at risk of developing hypertensive crises when using Adco Contromet tablets. It’s best advised consulting a physician before starting this medicine if one has been diagnosed with pheochromocytoma.
It is essential to note that not all individuals will experience these side effects, and some people may encounter different reactions altogether. If any adverse reaction occurs, it should be promptly reported to a healthcare professional who can provide appropriate guidance on how to manage them effectively.
In the event of an overdose
With Adco Contromet Tablet, it is important to seek immediate medical attention. Overdosing on this medication can lead to serious complications and requires prompt treatment.
The recommended approach for managing an overdose of Adco Contromet Tablet is symptomatic and supportive care. This means that healthcare professionals will focus on treating the symptoms caused by the excessive intake of the medication while providing necessary support to stabilize the patient’s condition.
Symptomatic treatment may involve measures such as:
Monitoring vital signs
Healthcare professionals will closely monitor the patient’s vital signs, including heart rate, blood pressure, and respiratory rate. This helps assess the severity of the overdose and guide further treatment decisions.
Administering intravenous fluids
If dehydration occurs as a result of the overdose, healthcare professionals may administer intravenous fluids to restore fluid balance and prevent complications.
Using medications to control adverse effects
In some cases, medications may be used to control any adverse effects experienced due to the overdose. These medications can help manage symptoms and prevent further complications.
The specific interventions used will depend on individual circumstances and the severity of symptoms observed in each case. It is crucial for patients, caregivers, or individuals who suspect someone has taken too much Adco Contromet Tablet without a prescription to immediately contact their local poison control center or emergency services for guidance regarding appropriate actions required based upon professional advice provided over a phone call.
Presentation and Manufacturer
Adco Contromet Tablet is available in various presentations to suit different preferences. The tablets are packed either in securitainers or blister packs, ensuring the safety and integrity of each tablet. This packaging option provides convenience for users who prefer a portable and easily accessible form.
For those who prefer liquid medication, Adco Contromet also offers syrup as an alternative presentation. The syrup comes packaged in amber glass bottles, which not only protects the contents from light but also adds a touch of elegance to its appearance.
It’s important to note that these different presentations cater to individual needs and preferences while maintaining the effectiveness of the medication itself.
The manufacturing company behind Adco Contromet Tablet is none other than Adcock Ingram Limited – a reputable pharmaceutical company with years of experience in producing high-quality medications. With their commitment to excellence, you can trust that every batch undergoes rigorous quality control measures before reaching your hands.
By choosing products manufactured by Adcock Ingram Limited like Adco Contromet Tablet, you can have peace of mind knowing that they adhere strictly to industry standards and regulations throughout their production process.
Frequently Asked Questions
1. What is the active ingredient in Adco Contromet Tablet?
The active ingredient in Adco Contromet Tablet is Metoclopramide monohydrochloride.
2. What is the recommended dosage for adults?
For adults, the recommended dosage of Adco Contromet Tablet is 10 mg taken every eight hours. However, it’s important to follow your healthcare professional’s instructions regarding dosing and duration of treatment.
3. What are the common side effects of Adco Contromet Tablet?
Common side effects associated with taking Adco Contromet Tablets may include tardive dyskinesia (a serious movement disorder), extrapyramidal symptoms, bowel upsets, drowsiness, fatigue, dizziness, restlessness, anxiety, galactorrhea (abnormal milk production), gynecomastia (enlargement of breast tissue in males), and transient increases in plasma aldosterone concentrations. It’s essential to consult a healthcare professional if you experience any concerning or persistent side effects while taking this medication.
4. Can Adco Contromet Tablet be used during pregnancy?
The use of metoclopramide during pregnancy is considered unsafe as teratogenicity has been demonstrated in animal studies. It should not be used during pregnancy unless specifically prescribed by a doctor after considering potential risks and benefits.
5. Are there any contraindications for using Adco Contromet Tablet?
Yes, there are certain contraindications for using Adco Contromet Tablet. It should not be used in cases where gastrointestinal conditions might be adversely affected, such as intestinal obstruction or immediately after surgery. It is also contraindicated in patients with phaeochromocytoma or convulsive disorders. Please remember to consult your healthcare professional before starting this medication.
6. How should Adco Contromet Tablet be stored?
Adco Contromet Tablet should be stored in a cool, dry place below 25°C. It is important to keep the medication out of reach and sight of children.
7. Can Adco Contromet Tablet interact with other medications?
Yes, Adco Contromet Tablet may interact with other medications. It is important to inform your healthcare provider about all the medications you are taking, including supplements and herbal products. This will help prevent any potential drug interactions or adverse effects.
8. Is Adco Contromet Tablet available over the counter?
No, Adco Contromet Tablet is not available over the counter. It must be prescribed by a healthcare professional after evaluating your medical condition and determining if it is suitable for you.
9. How long does it take for Adco Contromet Tablet to start working?
The onset of action of this medication may vary from person to person. In general, it can start working within 30 minutes to 1 hour after taking the tablet. However, the exact timeframe can depend on individual factors such as metabolism and body weight. If you do not experience improvement in your symptoms or if your condition worsens, a consultation with a healthcare professional is suggested.
10. Can Adco Contromet Tablet be used in children?
The dosage for children varies depending on their age, and it’s essential to discuss this with a healthcare provider before administering this medication to children. A doctor will determine the appropriate dose based on the specific needs and age of the child.
References
- https://www.sahpra.org.za/wp-content/uploads/2020/08/Adco-Contromet_PI_Adcock-Ingram_MCC-Format03-July-2020.pdf
- https://www.drugs.com/international/adco-contromet.html
- https://i-base.info/qa/10633/comment-page-4